Who portrays Karen Wheeler? Which actress embodies the role of Karen Wheeler in the series? Whom is the performer behind Karen Wheeler? Mrs. Wheeler is portrayed by whom? Who acts as the character of Karen the mother on the show? Whom is the talent personifying Karen the mother's character to life? Which performer takes on the role of Karen Mrs. Wheeler in the television show? Who acts Karen Mrs. Wheeler? Whom is the talented individual enacting Karen Wheeler on the series? What actress incarnates the character of Karen Wheeler to the screen?